MicroRNA29a Treatment Improves Early Tendon Injury
نویسندگان
چکیده
منابع مشابه
MicroRNA29a regulates IL-33-mediated tissue remodelling in tendon disease
MicroRNA (miRNA) has the potential for cross-regulation and functional integration of discrete biological processes during complex physiological events. Utilizing the common human condition tendinopathy as a model system to explore the cross-regulation of immediate inflammation and matrix synthesis by miRNA we observed that elevated IL-33 expression is a characteristic of early tendinopathy. Us...
متن کاملAutologous Platelet Rich Plasma Injection Improves Early Tendon Repair in Rabbits: A Histopathological and Biomechanical Study
Objective- The aim of this study was to investigate the PRP effects on the early time-period during tendon healing in rabbits DDF tendon. Design-Experimental study Animals- Twenty male New Zealand white rabbits Procedure-PRP samples were prepared using twice centrifugation method of modification of the Cuarsan...
متن کاملAdipose derived stromal vascular fraction improves early tendon healing: an experimental study in rabbits
Tendon never restores the complete biological and mechanical properties after healing. Bone marrow and recently adipose tissue have been used as the sources of mesenchymal stem cells, which have been proven to enhance tendon healing. Stromal vascular fraction (SVF), derived from adipose tissue by an enzymatic digestion, represents an alternative source of multipotent cells, which undergo differ...
متن کاملParecoxib impairs early tendon repair but improves later remodeling.
BACKGROUND Cyclooxygenase-2 inhibitors inhibit bone repair. HYPOTHESIS Cyclooxygenase inhibitors might also have a negative effect on early tendon repair, although a positive effect on late tendon repair previously has been shown. STUDY DESIGN Controlled laboratory study. METHODS Achilles tendon transection was performed on 80 rats. Sixty rats were given daily intramuscular injections of ...
متن کاملAbstract: Polydeoxyribonucleotide improves tendon healing following achilles tendon injury in rats
Tendon injuries are major musculoskeletal disorders. Polydeoxyribonucleotide activates the adenosine receptor subtype A2A, resulting in tissue growth and neogenesis. This experimental study confirms that polydeoxyribonucleotide can improve secretion of various growth factors, promote collagen synthesis, and restore tensile strength of the Achilles tendon in a rat model with Achilles tendon inju...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Molecular Therapy
سال: 2017
ISSN: 1525-0016
DOI: 10.1016/j.ymthe.2017.07.015